Clinical Pathology: Transfusion Medicine

• The AABB standards state that for blood collection, the volume of the collected blood should be proportional to the amount of anticoagulant/preservative solution that is in the collection container.

• In the United States, the volume of blood collected during routine phlebotomy is either 450mL ± 10% (405 to 495 mL) or 500 mL ±10% (450 to 550 mL).

• If 300 to 404 mL of whole blood is collected into an anticoagulant volume intended for 450 ± 10%, or if 333 to 449 mL of whole blood is collected into an anticoagulant volume intended for 500 mL ± 10%, RBCs prepared from the unit should be labeled “Red Blood Cells Low Volume.”

• No other components should be made from this low-volume collection.

• If the collection volume is less than 300 mL, the amount of anticoagulant must be proportionally decreased.

AABB: Standards for blood banks and transfusion services. 27th ed. Bethesda, MD: AABB; 2011.

 
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