Anatomic Pathology: Salivary Gland Pathology

• Mucous and serous secretory glands, identical to those of the parotid, submandibular, and sublingual (i.e., major) salivary glands, are present in the nasal cavity, paranasal sinuses, nasopharynx, oral cavity, oropharynx, hypopharynx, esophagus, larynx, trachea, and bronchi.

• The neoplastic lesions that arise in these minor salivary glands are of the same histologic types as those that occur in the major salivary glands.

• The reported distribution of these lesions varies according to different series. In most large series, minor salivary gland tumors originate more frequently in the oral cavity (especially the palate), relative to other sites.

• Among the major salivary glands, the parotid gland is the most common site of salivary gland tumors.

• The parotid gland is furthermore the most common site of salivary gland tumors (both benign and malignant lesions) overall.

Dardick I (ed): Salivary Gland Tumor Pathology.New York: Igaku-Shoin; 1996.

Ellis GL, Auclair PL: Atlas of Tumor Pathology—Tumors of the Salivary Glands, Fascicle 17, 3rd series.Washington, DC: Armed Forces Institute of Pathology, 1996.

Huvos AG, Paulino AFG: Salivary glands.In: Mills SE, Carter D, Greenson JK, Oberman HA, Reuter V, Stoller MH (eds): Sternberg’s Diagnostic Surgical Pathology, 4th ed. Philadelphia: Lippincott Williams & Wilkins, 2004, pp 933–962.

Rosai J: Major and minor salivary glands.In: Rosai J (ed): Rosai and Ackerman’s Surgical Pathology, 9th ed, Vol 1, Chs 9 and 10. St Louis: Mosby, 2004, pp 873–916.

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