Zygomycosis is an invasive necrotizing infection. While it is not a common pulmonary infection, when present it is usually acute and angioinvasive and is not the cause of a chronic mass lesion.
Zygomycosis is a rapidly invasive, necrotizing infection often with angioinvasion. It is associated with acidosis, and in diabetic patients with bouts of diabetic ketoacidosis.
The structures, because of their branching and empty appearance, can be mistaken for blood vessels, especially on hematoxylin and eosin stain;however, they are not vascular channels and therefore are not part of an endothelial neoplasm.
The structures are fungi, not the vasculature of a myxoid liposarcoma.
Some fragmented structures in cases of Zygomycosis can resemble foreign material or vegetable matter;however, the regular branching structures are characteristic of fungal hyphae.