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344) The fractional hemoglobin saturation (i.e., FO₂Hb) refers to the percentage of total hemoglobin that is saturated with oxygen. If the oxygen saturation (SO₂) is known, which one of the following choices identifies the two additional parameters necessary for calculating the FO₂Hb?

Carboxyhemoglobin and deoxyhemoglobin. Deoxyhemoglobin and methemoglobin. Sickle hemoglobin and methemoglobin. Sickle hemoglobin and deoxyhemoglobin. Carboxyhemoglobin and methemoglobin.

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• The total hemoglobin (Hb) level is composed of the oxy-, deoxy-, met-, and carboxy- forms of Hb.

• Oxy- and deoxy- forms of Hb are functional because they are able to bind oxygen and carbon dioxide.

• MetHb and carboxy Hb are nonfunctional with regards to oxygen-binding capacity.

• SO₂ corresponds to the percentage of Hb that is bound to oxygen, relative to the amount of functional Hb (oxy + deoxy Hb).

• FO₂ corresponds to the percentage of Hb that is bound to oxygen, relative to the amount of total Hb (functional + nonfunctional forms).

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Clinical Pathology: General Principles, Clinical Chemistry

344) The fractional hemoglobin saturation (i.e., FO2Hb) refers to the percentage of total hemoglobin that is saturated with oxygen. If the oxygen saturation (SO2) is known, which one of the following choices identifies the two additional parameters necessary for calculating the FO2Hb?

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344) The fractional hemoglobin saturation (i.e., FO₂Hb) refers to the percentage of total hemoglobin that is saturated with oxygen. If the oxygen saturation (SO₂) is known, which one of the following choices identifies the two additional parameters necessary for calculating the FO₂Hb?