Diagnosis: Sexually Transmitted Infections
• Chlamydia trachomatis is the most prevalent etiologic agent causing sexually transmitted infections in the United States, followed by Neisseria gonorrhoeae.
• The most serious sequelae resulting from untreated Chlamydia trachomatis and Neisseria gonorrhoeae occur among women in the form of pelvic inflammatory disease, ectopic pregnancy, infertility, and chronic pelvic pain.
• Despite the decline of gonorrhea and syphilis in the United States, the prevalence of these sexually transmitted infections is increasing among men who have sex with men.
• Lymphogranuloma venereum is a systemic infection caused by invasive strains of Chlamydia trachomatis serovars L1, L2, and L3.
• Dual therapy of (ceftriaxone or cefixime) plus (azithromycin or doxycycline) for confirmed gonorrhea infection in adults and adolescents is recommended to also provide Chlamydia trachomatis coverage.
