Diagnosis: Klinefelter syndrome
• Klinefelter syndrome patients are characterized by tall habitus, abnormal body proportions, and small and firm testes. They have a decrease in pubic and facial hair and a large percentage have gynecomastia.
• They have decreased spermatogenesis, can either be azoospermic or oligospermic, and frequently have problems of infertility.
• The histologic changes in the testes of Klinefelter syndrome patients include tubular hyalinization, a decrease or absence of germ cells in nonhyalinized tubules when present, and Leydig cell hyperplasia.
