Chondrosarcoma is the second most common primary malignancy of bone in adults, following osteosarcoma and metastatic neoplasms representing the most common malignancies overall.
Most chondrosarcomas arise de novo and are thought to originate from uncommitted precursor cells.
Because chondrosarcomas do not respond to chemotherapy and radiation therapy, surgery is the treatment of choice.
Chondrosarcoma most commonly affects the large, flat bones of the axial skeleton, such as the pelvis, scapula, and sternum, and less frequently affects the long bones.
Chondrosarcomas manifest as a radiolucent mass with endosteal scalloping and cortical thickening, often extending into the soft tissue.
